Couples with Recurrent Pregnancy Loss (RPL) are constantly searching for help, when 50% of them do not have clear etiology and many other aspects are controversial. The 2016 World Congress on Recurrent Pregnancy Loss is the perfect setting to get the most updated, state-of-the-art information on the latest developments in research and clinical practice in the main areas of recurrent pregnancy loss. The world leaders in RPL will gather to give update lectures in all spectra of RPL and this opportunity should not be missed.